At a glance
Sequence
Ala-Glu-Asp-Gly
Molecular Weight
C14H22N4O9
CAS Number
307297-39-8
Purity
≥99%
Receptor
Telomerase modulation
Molecular Weight
390.4 Da
Reported Half-Life
~minutes
Storage
-20°C lyophilized
Reconstitution
BAC water
Overview
Longevity peptides are studied for their effects on mitochondrial function, telomere biology, cellular senescence, and redox balance. They often modulate sirtuin activity, cardiolipin integrity, or senescent-cell clearance.
Epitalon is studied for its activity at Telomerase modulation, with a reported half-life of ~minutes. The compound is supplied as a lyophilized powder and reconstituted with bac water prior to use in laboratory research.
Mechanism of Action
Sirtuin / AMPK activation, mitochondrial membrane stabilization, or FOXO/p53 disruption depending on target.
In published in-vitro work, Epitalon engages Telomerase modulation to initiate downstream signaling. The reported half-life of ~minutes informs typical dosing intervals in experimental protocols.
Research Applications
- Mitochondrial respiration (Seahorse) experiments
- Telomere length and telomerase assays
- Senescent cell clearance models
- Oxidative stress and glutathione recycling studies
Handling & Reconstitution
Reference guidance for laboratory handling.
- Storage: -20°C lyophilized. Avoid repeated freeze-thaw cycles.
- Reconstitution: BAC water. Add diluent slowly down the side of the vial; gentle swirl, do not shake.
- Stability: Once reconstituted, store at 2–8°C and use within 14–28 days depending on peptide stability.
- Working solution: Calculate target concentration before reconstitution. Our calculator can help.
Quality & Verification
- Every batch of Epitalon we ship is third-party tested by an ISO-accredited lab. Each order arrives with a batch-matched Certificate of Analysis showing HPLC purity (≥99%), mass spectrometry confirmation of 390.4 Da, and endotoxin / bioburden screening where applicable.
Related Entries
Senolytic research
Antioxidant pathway research
NAD metabolism research
Mitochondrial protection research
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≥99% purity · third-party tested · ships from the USA